STEREOCONTROLLED TOTAL SYNTHESIS OF GALACTOSTATIN FROM SERINE

被引：21

作者：

DONDONI, A

MERINO, P

PERRONE, D

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 21期

关键词：

D O I：

10.1039/c39910001576

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient stereoselective total synthesis of (-)-galactostatin (-)-1 from N-tert-butoxycarbonyl-2,3-isopropylidene L-serine methyl ester (21% overall yield) is described via thiazole intermediates serving as protected aldehydes; the parallel synthesis of the natural antipole (+)-1 starts from D-serine.

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页码：1576 / 1578

页数：3

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