ABILITY OF BKME (BLEACHED KRAFT MILL EFFLUENT) EXPOSED WHITE SUCKERS (CATOSTOMUS-COMMERSONI) TO SYNTHESIZE STEROID-HORMONES

被引：22

作者：

GAGNON, MM ^{[1
]}

DODSON, JJ ^{[1
]}

HODSON, PV ^{[1
]}

机构：

[1] CANADA CTR INLAND WATERS,BURLINGTON L7R 4A6,ON,CANADA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1994年 / 107卷 / 02期

基金：

加拿大自然科学与工程研究理事会;

关键词：

STEROID HORMONES; WHITE SUCKER; BKME; EROD; CATOSTOMUS COMMERSONI;

D O I：

10.1016/1367-8280(94)90050-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Steroid synthesis was stimulated in white suckers to study the impact of bleached kraft mill effluent (BKME). BKME-exposed male suckers reached similar testosterone levels, but lower 11-ketotestosterone levels relative to non-exposed fish. BKME-exposed females reached higher levels of testosterone but similar levels of 17 beta-estradiol, relative to non-exposed females. Ethoxyresorufin O-deethylase (EROD) activity was depressed in females secreting 17 beta-estradiol. Steroid synthesis by isolated ovarian follicles from exposed and non-exposed females was similar, suggesting that the origin of different steroid levels in BKME-exposed females is external to the gonad.

引用

页码：265 / 273

页数：9

共 23 条

[1]

Donaldson E.M., 1983, FISH PHYSL

[2]

GAGNON MM, 1993, IN PRESS CAN J FISH

[3]

GAGNON MM, 1993, UNPUB NATURAL BKME I

[4] REGULATION OF DISCHARGE OF ORGANOCHLORINES FROM PULP-MILLS IN CANADA [J].