THE ALPHA-KETO ESTER APPROACH TO CARBAPENEMS - THE SYNTHESIS OF CARBAPENEMS WITH CARBON LINKED C-2 SIDE-CHAINS

被引：4

作者：

FEIGELSON, GB

机构：

[1] Global Chemical Sciences Wyeth-Ayerst Research Pearl River

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 41期

关键词：

D O I：

10.1016/0040-4039(95)01580-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carbapenems with carbon linked side-chains at C-2 were prepared via the Lewis acid mediated cyclization of an alpha-keto ester bearing beta-lactam.

引用

收藏

页码：7407 / 7410

页数：4

相关论文

共 12 条

[1] A NEW ROUTE TO PENEMS AND CARBAPENEMS
BATTISTINI, C
SCARAFILE, C
FOGLIO, M
FRANCESCHI, G
[J]. TETRAHEDRON LETTERS, 1984, 25 (22) : 2395 - 2398
[2] OXIDATIVE HYDROLYSIS OF 1,3-DITHIANE DERIVATIVES TO CARBONYL COMPOUNDS USING N-HALOSUCCINIMIDE REAGENTS
COREY, EJ
ERICKSON, BW
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (23) : 3553 - &
[3] SYNTHESIS OF CARBAPENEMS WITH CARBON SUBSTITUENTS AT C-3 USING A WITTIG APPROACH
DEVRIES, JG
HAUSER, G
SIGMUND, G
[J]. TETRAHEDRON LETTERS, 1984, 25 (52) : 5989 - 5992
[4] DIFURIA F, 1990, GAZZ CHIM ITAL, V120, P165
[5] DININNO F, 1993, Patent No. 5208328
[6] DININNO F, Patent No. 94055669
[7] DININNO F, 1993, Patent No. 5214139
[8] A NEW STRATEGY FOR THE SYNTHESIS OF CARBAPENEMS - A FORMAL TOTAL SYNTHESIS OF (+)-THIENAMYCIN
FEIGELSON, GB
[J]. TETRAHEDRON LETTERS, 1993, 34 (30) : 4747 - 4750
[9] FEIGELSON GB, 1993, Patent No. 5189158
[10] STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE 2-ARYLCARBAPENEM SERIES - SYNTHESIS OF 1-METHYL-2-ARYLCARBAPENEMS
GUTHIKONDA, RN
CAMA, LD
QUESADA, M
WOODS, MF
SALZMANN, TN
CHRISTENSEN, BG
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (05) : 871 - 880