SYNTHETIC APPROACHES TO ADRIAMYCIN .2. DEGRADATION OF DAUNORUBICIN TO A NON-ASYMMETRIC TETRACYCLIC KETONE AND REFUNCTIONALIZATION OF A-RING TO ADRIAMYCIN

被引：141

作者：

SMITH, TH ^{[1
]}

FUJIWARA, AN ^{[1
]}

LEE, WW ^{[1
]}

WU, HY ^{[1
]}

HENRY, DW ^{[1
]}

机构：

[1] STANFORD RES INST,DEPT BIOORGAN CHEM,MENLO PK,CA 94025

来源：

关键词：

D O I：

10.1021/jo00443a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3653 / 3660

页数：8

共 40 条

[1] TOTAL SYNTHESIS OF ANTITUMOR ANTIBIOTIC DAUNORUBICIN - COUPLING OF SUGAR AND AGLYCONE
ACTON, EM
FUJIWARA, AN
HENRY, DW
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (06) : 659 - 660
[2] ARCAMONE F, 1975, CANCER CHEMOTH REP 3, V6, P123
[3] SYNTHESIS AND ANTITUMOR PROPERTIES OF NEW GLYCOSIDES OF DAUNOMYCINONE AND ADRIAMYCINONE
ARCAMONE, F
PENCO, S
VIGEVANI, A
REDAELLI, S
FRANCHI, G
DIMARCO, A
CASAZZA, AM
DASDIA, T
FORMELLI, F
NECCO, A
SORANZO, C
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (07) : 703 - 707
[4] DAUNOMYCIN .I. STRUCTURE OF DAUNOMYCINONE
ARCAMONE, F
BARBIERI, W
FRANCESC.G
MONDELLI, R
OREZZI, P
CASSINELLI, G
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (23) : 5334 - &
[5] ARCAMONE F, 1969, TETRAHEDRON LETT, P1007
[6] ARCAMONE F, 1969, CHIM IND-MILAN, V51, P834
[7] Arcamone F., 1974, [No title captured], Patent No. [US 3803124, 3803124]
[8] ARCAMONE F, 1976, Patent No. 842930
[9] BABLER JH, 1974, TETRAHEDRON LETT, P351
[10] ALPHA-METHOXYVINYLLITHIUM AND RELATED METALATED ENOL ETHERS - PRACTICAL REAGENTS FOR NUCLEOPHILIC ACYLATION
BALDWIN, JE
HOFLE, GA
LEVER, OW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (22) : 7125 - 7127