RUBELLA-VIRUS - INTRACELLULAR POLYPEPTIDE-SYNTHESIS

被引：13

作者：

CHANTLER, JK

机构：

[1] Division of Medical Microbiology, University of British Columbia, Vancouver

来源：

VIROLOGY | 1979年 / 98卷 / 01期

关键词：

D O I：

10.1016/0042-6822(79)90548-8

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Rubella virus (RV) grown in RK13 cells induces a range of polypeptides ranging in molecular weights from 109K to 28K. As RV does not inhibit host metabolism, detection of these requires the use of elevated concentrations of NaCL in the labelling medium to selectively inhibit cellular translation. Several of the viral polypeptides, including p109, p92, and p72 are transient high molecular weight species which may represent precursors of functional viral polypeptides. Only five or six of the polypeptides are synthesized in large amounts at late stages of infection and these probably include the structural components. © 1979.

引用

页码：275 / 278

页数：4

共 10 条

[1]

BURKE DC, 1975, MED BIOL, V53, P352

[2] USE OF HYPERTONICITY TO SELECTIVELY INHIBIT HOST TRANSLATION IN MURINE CYTOMEGALOVIRUS-INFECTED CELLS [J].