RESPONSE OF PIG SKIN TO SINGLE AND FRACTIONATED HIGH DOSE-RATE AND CONTINUOUS LOW DOSE-RATE CS-137-IRRADIATION .3. RE-EVALUATION OF THE CRE SYSTEM AND THE TDF SYSTEM ACCORDING TO THE PRESENT FINDINGS

被引：12

作者：

TURESSON, I ^{[1
]}

NOTTER, G ^{[1
]}

机构：

[1] GOTHENBURG UNIV, SAHLGRENS HOSP, DEPT RADIAT THERAPY, S-41345 GOTHENBURG, SWEDEN

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1979年 / 5卷 / 10期

关键词：

Continuous irradiation; Cumulative radiation effect (CRE); Dose rate; Fractionated irradiation; Pig skin; Time dose fractionation factors (TDF);

D O I：

10.1016/0360-3016(79)90560-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Application of the cumulative radiation effect (CRE) and time dose fractionation factors (TDF) systems on the dose-effect data from single and fractionated irradiation at high dose rate and continuous irradiation at low dose rate on pig skin revealed that significant corrections of these empirical models are necessary. There is evidence for modification of the CRE and TDF-formula for fractionated high dose-rate irradiation concerning late effects on normal tissue. The pig skin result indicated a value of the normalizing constant of 0.57 and 2.02 in the CRE and TDF-formulae for continuous irradiation instead of the proposed value of 0.80 and 1.57 respectively. The practical consequences for prediction of equivalent normal tissue reactions for fractionated high dose-rate and continuous low-dose-rate irradiation by the CRE and TDF systems will be elucidated. © 1979.

引用

页码：1773 / 1779

页数：7

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