IDENTIFICATION OF 34 APOLIPOPROTEIN(A) ISOFORMS - DIFFERENTIAL EXPRESSION OF APOLIPOPROTEIN(A) ALLELES BETWEEN AMERICAN BLACKS AND WHITES

被引:217
作者
MARCOVINA, SM
ZHANG, ZH
GAUR, VP
ALBERS, JJ
机构
[1] Department of Medicine, Northwest Lipid Research Laboratorics, University of Washington, Seattle, WA
关键词
D O I
10.1006/bbrc.1993.1343
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A total of 34 different apo(a) isoforms was identified in a population sample of 806 American Whites and 701 American Blacks by a high resolution SDS-agarose gel electrophoretic method followed by immunoblotting. Among the 1507 individuals tested, 79% revealed double-banded phenotypes and 21% single-banded phenotypes. The frequencies of the apo(a) isoforms differed between American Blacks and Whites (p <0.001). © 1993 Academic Press.
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页码:1192 / 1196
页数:5
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