STUDIES DIRECTED TOWARDS THE TOTAL SYNTHESIS OF RHIZOXIN - STEREOSELECTIVE SYNTHESIS OF C-12 TO C-18 SEGMENT

被引：28

作者：

RAO, AVR

BHANU, MN

SHARMA, GVM

机构：

[1] Indian Institute of Chemical Technology, Hyderabad

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 04期

关键词：

BUTANOLIDE CHIRAL TEMPLATE; CHIRAL CARBINOL; INTRAMOLECULAR RADICAL CYCLIZATION; VINYL GRIGNARD REACTION;

D O I：

10.1016/S0040-4039(00)61659-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral carbinol 5, made by a titanocene mediated ring opening of epoxy alcohol 11, was converted via an intramolecular radical cyclisation into a 'butanolide template' which was then transformed to the C-12 to C-18 segment 2 of rhizoxin (1).

引用

页码：707 / 710

页数：4

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