KINETICS OF HYDROLYSIS OF THE VINYL ETHER FUNCTIONAL-GROUP OF THE STABLE, BIOACTIVE PROSTACYCLIN ANALOG TAPROSTENE (CG-4203)

被引：6

作者：

CHIANG, Y

KRESGE, AJ

SEIPP, U

WINTER, W

机构：

[1] UNIV TORONTO,DEPT CHEM,TORONTO M5S 1A1,ONTARIO,CANADA

[2] GRUNENTHAL GMBH,CTR RES,D-5100 AACHEN,FED REP GER

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1988年 / 53卷 / 11期

关键词：

D O I：

10.1021/jo00246a028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2552 / 2555

页数：4

共 26 条

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[2] BATES RG, 1973, DETERMINATION PH THE, P49
[3] (Z)-6,9-EPOXYNON-5-ENOIC ACID - A SIMPLE-MODEL WHICH MIMICS THE UNUSUAL HYDROLYTIC LABILITY OF PROSTACYCLIN
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YA, Y
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (17) : 1366 - 1368
[4] REEXAMINATION OF THE ALLEGED VINYL ETHER HYDROLYSIS REACTION OF 9-METHOXY-1-OXACYCLONON-2-ENE - DISPROOF OF REVERSIBLE CARBON PROTONATION
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CHIANG, Y
CHWANG, WK
KRESGE, AJ
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TANG, YS
YIN, Y
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (12) : 3787 - 3788
[5] VINYL ETHER HYDROLYSIS .12. USE OF CIS-TRANS ISOMERISM TO PROBE REACTION-MECHANISM
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YOUNG, CI
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1978, 56 (04): : 461 - 464
[6] ACID-CATALYZED HYDROLYSIS OF PROSTACYCLIN - ORIGIN OF THE UNUSED LABILITY
CHIANG, Y
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CHO, MJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1979, (03) : 129 - 130
[7] PROSTACYCLIN - EVIDENCE THAT INTRAMOLECULAR GENERAL-ACID CATALYSIS BY ITS CARBOXYLIC-ACID GROUP IS RESPONSIBLE FOR THE EXTRA HYDROLYTIC LABILITY
CHIANG, Y
CHO, MJ
EUSER, BA
KRESGE, AJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (14) : 4192 - 4196
[8] CHEMICAL STABILITY OF PROSTACYCLIN (PGI2) IN AQUEOUS-SOLUTIONS
CHO, MJ
ALLEN, MA
[J]. PROSTAGLANDINS, 1978, 15 (06): : 943 - 954
[9] VINYL ETHER HYDROLYSIS .8. ELECTROSTATIC EFFECTS PRODUCED BY NEGATIVELY CHARGED CATALYSTS
CHWANG, WK
ELIASON, R
KRESGE, AJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (03) : 805 - 808
[10] FLOHE L, 1983, ARZNEIMITTEL-FORSCH, V33-2, P1240

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