HISTIDINE-STIMULATED ACID-SECRETION IN THE CONSCIOUS RAT IS MEDIATED BY AMINO-ACID-UPTAKE SYSTEM-N

被引：5

作者：

DIMALINE, R

WILKINSON, M

TALBOT, SJ

机构：

来源：

EXPERIMENTAL PHYSIOLOGY | 1990年 / 75卷 / 05期

关键词：

D O I：

10.1113/expphysiol.1990.sp003451

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The characteristics of sodium‐dependent, histidine‐stimulated gastric acid secretion were studied in the conscious gastric‐fistulated rat. Intragastric L‐histidine, but not glutamine, asparagine, glutamic acid or glycine, stimulated acid secretion. The histidine‐stimulated acid secretion was inhibited by the presence of glutamine or asparagine, but not by glutamic acid or glycine. The substitution of lithium for sodium in the gastric perfusate was tolerated. Together with previous data, the results indicate that an N‐like amino acid uptake system mediates histidine‐stimulated acid secretion in the conscious rat. © 1990 The Physiological Society

引用

页码：717 / 720

页数：4

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