THE DOMINANT SELF AND THE CRYPTIC SELF - SHAPING THE AUTOREACTIVE T-CELL REPERTOIRE

被引：109

作者：

GAMMON, G ^{[1
]}

SERCARZ, EE ^{[1
]}

BENICHOU, G ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,DEPT MICROBIOL & MOLEC GENET,LOS ANGELES,CA 90024

来源：

IMMUNOLOGY TODAY | 1991年 / 12卷 / 06期

关键词：

D O I：

10.1016/0167-5699(91)90052-U

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Deletion of autoreactive T cells during the induction of self tolerance has been directly demonstrated. However, it is still relatively easy to detect self reactivity in normal healthy animals. In this article, Guy Gammon, Eli Sercarz and Gilles Benichou speculate on which T cells may escape tolerance induction and discuss how these cells could subsequently be involved in autoimmunity.

引用

页码：193 / 195

页数：3

共 17 条

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