SYNTHESIS OF (-)-AURICULARIC ACID AND ITS C-4 EPIMER - THE ABSOLUTE-CONFIGURATION OF AURICULARIC ACID

被引：14

作者：

ABAD, A

ARNO, M

PEIRO, M

ZARAGOZA, RJ

机构：

[1] Departamento de Química Orgánica. Facultad, Químicas. Universitat de Valencia, 46100 Burjassot, Valencia

来源：

TETRAHEDRON | 1991年 / 47卷 / 23期

关键词：

D O I：

10.1016/S0040-4020(01)80907-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of (-)-auricularic acid (2a) starting from methyl (+)-13-oxopodocarp-8(14)-en-19-oate (3a) and a synthesis of its C-4 epimer (2b) starting from methyl (+)-13-oxopodocarp-8(14)-en-18-oate (3b) are described. The absolute configuration of natural auricularic acid is established as (4R, 5S, 8S, 9R, 10S, 14S).

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页码：3829 / 3844

页数：16

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