ELECTROCARDIOGRAPHIC ALTERATIONS DURING TREATMENT OF MUCOCUTANEOUS LEISHMANIASIS WITH MEGLUMINE ANTIMONIATE AND ALLOPURINOL

被引：28

作者：

ANTEZANA, G ^{[1
]}

ZEBALLOS, R ^{[1
]}

MENDOZA, C ^{[1
]}

LYEVRE, P ^{[1
]}

VALDA, L ^{[1
]}

CARDENAS, F ^{[1
]}

NORIEGA, I ^{[1
]}

UGARTE, H ^{[1
]}

DEDET, JP ^{[1
]}

机构：

[1] UNIV MAYOR SAN ANDRES,HOSP CLIN,DEPT DERMATOL,LA PAZ,BOLIVIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1992年 / 86卷 / 01期

关键词：

D O I：

10.1016/0035-9203(92)90427-E

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The electrocardiographic (ECG) changes in Bolivian patients with mucocutaneous leishmaniasis, treated with meglumine antimoniate and allopurinol, were evaluated. Electric changes due to the antimonial compound appeared in 45% of the patients, and consisted of repolarization alteration, principally affecting the T wave and the S-T segment. The changes disappeared within 2 months following the end of the antimonial treatment. In patients with associated Chagas disease and leishmaniasis, antimonial therapy did not aggravate the ECG changes characteristic of Chagasic cardiopathy.

引用

页码：31 / 33

页数：3

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