VERTICAL TRANSMISSION OF NEOSPORA-CANINUM IN DOGS

被引：53

作者：

COLE, RA ^{[1
]}

LINDSAY, DS ^{[1
]}

BLAGBURN, BL ^{[1
]}

SORJONEN, DC ^{[1
]}

DUBEY, JP ^{[1
]}

机构：

[1] AUBURN UNIV, COLL VET MED, DEPT PATHOBIOL, AUBURN, AL 36849 USA

来源：

JOURNAL OF PARASITOLOGY | 1995年 / 81卷 / 02期

关键词：

D O I：

10.2307/3283921

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Herein we report the development of a canine model to examine transplacental and/or transmammary transmission of Neospora caninum. Six pregnant bitches were experimentally infected with N. caninum on day 21 of gestation. One bitch successfully delivered a litter of 3 live pups. These pups showed slight proprioception deficits, increased muscle tone, and spasticity in both pelvic limbs; however, N. caninum was neither demonstrated by bioassay in cell culture nor seen in histological sections of tissues from these pups. The remaining 5 bitches aborted. Neospora caninum was isolated from tissues of 4 of the experimentally infected bitches and pups from 2 of the miscarried litters. Experimental infections of 2 litters of 5-day-old nursing pups produced variable results. Neospora caninum was isolated from 2 of 2 inoculated pups in 1 litter and 3 of 6 inoculated pups in the second litter.

引用

页码：208 / 211

页数：4

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