MEMBRANE-BOUND PHOSPHOTYROSYL-PROTEIN PHOSPHATASE-ACTIVITY IN HUMAN-ERYTHROCYTES - DEPHOSPHORYLATION OF MEMBRANE BAND-3 PROTEIN

被引：30

作者：

CLARI, G

BRUNATI, AM

MORET, V

机构：

[1] UNIV VERONA, IST CHIM BIOL, STRADA LE GRAZIE, I-37100 VERONA, ITALY

[2] UNIV PADUA, IST CHIM BIOL, I-35131 PADUA, ITALY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1987年 / 142卷 / 02期

关键词：

D O I：

10.1016/0006-291X(87)90314-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Human erythrocyte membrane exhibit, in addition to "acid" p-nitrophenyl-phophatase activity, remarkable phosphotyrosyl-protein phosphatase activity, assayed on synthetic polymer poly (Glu-Tyr) 4:1, previously phosphorylated on Tyr residues by rat spleen tyrosine-protein kinase. The results reported here indicate that such a 32P-Tyr-phosphatase activity, rather than p-nitrophenyl-phosphate, is involved in the dephosphorylation of transmembrane band 3 protein on 32P-tyrosine residues.

引用

页码：587 / 594

页数：8

共 18 条

[1]

BEUTLER E, 1976, J LAB CLIN MED, V88, P328

[2] INTERACTIONS OF THE HUMAN RED-CELL MEMBRANE TYROSINE KINASE WITH HEPARIN [J].