INVITRO BIOCOMPATIBILITY OF POLYETHERETHERKETONE AND POLYSULFONE COMPOSITES

被引:190
作者
WENZ, LM
MERRITT, K
BROWN, SA
MOET, A
STEFFEE, AD
机构
[1] CASE WESTERN RESERVE UNIV,DEPT BIOMED ENGN,CLEVELAND,OH 44106
[2] CLEVELAND SPINE & ARTHRIT CTR,CLEVELAND,OH
来源
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1990年 / 24卷 / 02期
关键词
Biomedical Engineering--Surgical Implants - Composite Materials--Biocompatibility - Plastics; Reinforced--Carbon Fiber - Polysulfones;
D O I
10.1002/jbm.820240207
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Short carbon fiber reinforced composites could potentially replace some of the metal alloys used in orthopedic implants. In particular, polysulfone and, more recently, polyetheretherketone have been considered as the matrix material for carbon fiber reinforced composite implant materials. ASTM standards F813 and F619 for direct contact cell culture evaluation and extraction were employed to determine the in vitro biocompatibility of a carbon fiber composite of polyetheretherketone, PEEK, in comparison to a carbon fiber reinforced polysulfone composite. The cell cultures were assessed qualitatively by microscopy and quantitatively using an enzyme assay to determine cytotoxicity. Overall, the cellular response to the PEEK and polysulfone composites were negligible indicating that further in vivo studies with these materials are appropriate. Copyright © 1990 John Wiley & Sons, Inc.
引用
收藏
页码:207 / 215
页数:9
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