SYNTHESIS AND REACTIVITY OF 2-(1,3-DITHIAN-2-YL)INDOLES .3. INFLUENCE OF THE INDOLE PROTECTIVE N-PHENYLSULFONYL GROUP

被引：22

作者：

RUBIRALTA, M ^{[1
]}

DIEZ, A ^{[1
]}

REIG, I ^{[1
]}

CASTELLS, J ^{[1
]}

BETTIOL, JL ^{[1
]}

GRIERSON, DS ^{[1
]}

HUSSON, HP ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91190 GIF SUR YVETTE,FRANCE

来源：

HETEROCYCLES | 1990年 / 31卷 / 01期

关键词：

D O I：

10.3987/COM-89-5240

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Formation of the anion of 2-(1,3-dithian-2-yl)indoles was shown to be possible when the indole nitrogen is protected by a p-methoxyphenylsulfonyl group. In contrast to the corresponding N-phenylsulfonylindole dithiane 1, the anion of dithiane 2 reacts efficiently with electrophiles.The influence of the indole protective group on the metallation of 2-bis(ethylthio)-methyl-1-(phenylsulfonyl)indole (14) and the corresponding sulfoxide 24 with n-butyllithium is also reported. © 1990.

引用

页码：173 / 186

页数：14

共 15 条

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