STEREOCHEMICAL STUDIES ON ESPERAMICINS - THE ABSOLUTE-CONFIGURATION OF THEIR BICYCLIC AGLYCONE

被引：7

作者：

GOLIK, J ^{[1
]}

KRISHNAN, B ^{[1
]}

DOYLE, TW ^{[1
]}

VANDUYNE, G ^{[1
]}

CLARDY, J ^{[1
]}

机构：

[1] CORNELL UNIV,DEPT CHEM,BAKER LAB,ITHACA,NY 14853

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)60003-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Single crystal x-ray diffraction analyses revealed the relative configuration of esperamicin X and the absolute configuration of 2-deoxy fucose, a fragment present in all known esperamicins. Comparison of the CD curves for esperamicins X and Z gave evidence for their identical chirality. Based on these data the absolute stereochemistry of [7,3,1] bicyclic aglycone of esperamicins has been assigned as C-1 (S), C-8 (S). and C-12 (S).

引用

页码：6049 / 6052

页数：4

共 6 条

[1] STEREOCHEMICAL STUDIES ON ESPERAMICINS - DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF HYDROXYAMINO SUGAR FRAGMENT [J].