METABOLISM OF ISONIAZID AND FREE HYDRAZINE FORMATION IN ISOLATED RAT HEPATOCYTES

被引：7

作者：

HIRATA, M

ASO, Y

HSU, KY

TABATA, T

NODA, A

IGUCHI, S

机构：

[1] KYUSHU UNIV,FAC PHARMACEUT SCI,HIGASHI KU,FUKUOKA 812,JAPAN

[2] SHIONOGI & CO LTD,SHIONOGI RES LAB,FUKUSHIMA KU,OSAKA 553,JAPAN

来源：

JOURNAL OF PHARMACOBIO-DYNAMICS | 1981年 / 4卷 / 02期

关键词：

D O I：

10.1248/bpb1978.4.145

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：145 / 147

页数：3

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[3]

Moldeus P, 1978, Methods Enzymol, V52, P60

[4] ISONIAZID AND IPRONIAZID - ACTIVATION OF METABOLITES TO TOXIC INTERMEDIATES IN MAN AND RAT [J].

NELSON, SD ;

MITCHELL, JR ;

TIMBRELL, JA ;

SNODGRASS, WR ;

CORCORAN, GB .

SCIENCE, 1976, 193 (4256) :901-903

[5]

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[6]

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[7]

PETERS JH, 1965, J PHARMACOL EXP THER, V150, P298

[8]

SATOH T, 1971, BIOCHEM PHARMACOL, V20, P504

[9]

TIMBRELL JA, 1979, DRUG METAB DISPOS, V7, P237

[10]

Weber W.W, 1973, METAB CONJUGATION, P249

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