CROCACIN, A NEW ELECTRON-TRANSPORT INHIBITOR FROM CHONDROMYCES-CROCATUS (MYXOBACTERIA) - PRODUCTION, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

被引：94

作者：

KUNZE, B ^{[1
]}

JANSEN, R ^{[1
]}

HOFLE, G ^{[1
]}

REICHENBACH, H ^{[1
]}

机构：

[1] GESELL BIOTECHNOL FORSCH MBH,CHEM NAT PROD,D-38124 BRAUNSCHWEIG,GERMANY

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 08期

关键词：

D O I：

10.7164/antibiotics.47.881

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Crocacin was isolated from the biomass of the myxobacterium Chondromyces crocatus, strain Cm c3. It inhibited the growth of a few Gram-positive bacteria and a wide spectrum of yeasts and molds. In beef heart submitochondrial particles, crocacin blocked the electron transport within the bc(1)-segment (complex III) and caused a red shift in the reduced spectrum of cytochrome b with a maximum at 569 nm.

引用

页码：881 / 886

页数：6

共 9 条

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