STEREOSPECIFICITY OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHETASE REACTION

被引:17
作者
ONDERKA, DK
FLOSS, HG
机构
[1] Department of Medicinal Chemistry and Pharmacognosy, Purdue University, Lafayette
关键词
D O I
10.1016/0006-291X(69)90694-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
As shown with PEP tritiated asymmetrically at C-3, the DAHP synthetase reaction is at least 60-70% stereospecific with respect to C-3 of PEP. This result excludes the intermediary formation of a methyl group at this carbon atom as an obligatory step in the reaction. © 1969.
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页码:801 / &
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