CYCLISATION OF N-PROP-2-YNYLBENZYLAMINES - PREPARATION OF A 1,2-DIHYDROISOQUINOLINE AND A 2-BENZAZEPINE

被引：15

作者：

BROOKS, JR

HARCOURT, DN

机构：

[1] School of Pharmacy, Bath University of Technology, Bath, Somerset

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 04期

关键词：

D O I：

10.1039/j39690000625

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Prop-2-ynylbenzylamines undergo acid-catalysed ring-closure to form heterocyclic bases. The results of two cyclisations are reported. With a terminal acetylene group, the product was a 1,2-dihydroisoquinoline. In contrast, with a phenyl-substituted acetylene the reaction gave a 2-benzazepine. Mass spectra have been obtained for both products, and a reaction mechanism is postulated.

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页码：625 / +

页数：1

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