ARACHIDONIC-ACID AGGREGATES NEUTROPHILS

被引：29

作者：

OFLAHERTY, JT ^{[1
]}

SHOWELL, HS ^{[1
]}

BECKER, EL ^{[1
]}

WARD, PA ^{[1
]}

机构：

[1] UNIV CONNECTICUT, CTR HLTH, FARMINGTON, CT 06032 USA

来源：

INFLAMMATION | 1979年 / 3卷 / 04期

关键词：

D O I：

10.1007/BF00913500

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Arachidonic acid, but not several structurally similar fatty acids, stimulated [human] neutrophils in suspension to aggregate; this effect was blocked by 5,8,11,14-eicosatetraynoic acid, an inhibitor of arachidonic acid metabolism. Analogous to platelets, arachidonate may be a precursor of active metabolites which mediate neutrophil responses.

引用

页码：431 / 436

页数：6

共 14 条

[1] METABOLISM OF (C-14) ARACHIDONIC-ACID BY HUMAN PLATELETS
BILLS, TK
SMITH, JB
SILVER, MJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 424 (02) : 303 - 314
[2] BORGEAT P, 1976, J BIOL CHEM, V251, P7816
[3] THROMBOXANE GENERATION BY HUMAN PERIPHERAL-BLOOD POLYMORPHONUCLEAR LEUKOCYTES
GOLDSTEIN, IM
MALMSTEN, CL
KINDAHL, H
KAPLAN, HB
RADMARK, O
SAMUELSSON, B
WEISSMANN, G
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1978, 148 (03) : 787 - 792
[4] Granstrom E, 1978, Adv Prostaglandin Thromboxane Res, V5, P1
[5] CHEMOTACTIC ROLE FOR PROSTAGLANDINS RELEASED FROM POLYMORPHONUCLEAR LEUKOCYTES DURING PHAGOCYTOSIS
HIGGS, GA
MCCALL, E
YOULTEN, LJF
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1975, 53 (04) : 539 - 546
[6] CHEMOTACTIC ACTIVITY OF THROMBOXANE B-2, PROSTAGLANDINS AND THEIR METABOLITES FOR POLYMORPHONUCLEAR LEUKOCYTES
KITCHEN, EA
BOOT, JR
DAWSON, W
[J]. PROSTAGLANDINS, 1978, 16 (02): : 239 - 244
[7] OFLAHERTY JT, 1978, AM J PATHOL, V92, P155
[8] OFLAHERTY JT, 1978, AM J PATHOL, V90, P537
[9] Sahu S, 1977, Inflammation, V2, P47, DOI 10.1007/BF00920874
[10] PERSISTENCE OF THROMBOXANE A2-LIKE MATERIAL AND PLATELET RELEASE-INDUCING ACTIVITY IN PLASMA
SMITH, JB
INGERMAN, C
SILVER, MJ
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1976, 58 (05) : 1119 - 1122

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