EVALUATION OF THE EFFICACY OF DIFFERENT ANTIBIOTICS IN INHIBITING COLONIZATION OF VIBRIO-CHOLERAE O1 IN THE RABBIT INTESTINE

被引：2

作者：

CHAKRABARTI, MK

BHATTACHARYA, MK

SINHA, AK

CHATTERJEE, DC

BHATTACHARYA, SK

机构：

[1] National Institute of Cholera and Enteric Diseases, Calcutta

来源：

ZENTRALBLATT FUR BAKTERIOLOGIE-INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY VIROLOGY PARASITOLOGY AND INFECTIOUS DISEASES | 1993年 / 278卷 / 01期

关键词：

D O I：

10.1016/S0934-8840(11)80280-X

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The efficacy of ciprofloxacin, norfloxacin and tetracycline in prevention of colonisation of V. cholerae 01 in the rabbit intestine were tested. V. cholerae O1 highly colonised the gut of rabbits which did not receive any antibiotic. All antibiotics tested inhibited the colonisation of V. cholerae 01 within the rabbit intestine. Moreover, ciprofloxacin and norfloxacin were found to be as effective as tetracycline suggesting that these drugs should be subjected to clinical trials for the treatment of cholera in comparison with tetracycline.

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页码：69 / 72

页数：4

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