PERHALOGENMETHYLMERCAPTO-HETEROCYCLEN, .9. (PERCHLORMETHYLMERCAPTO)PYRIDINE AND (PERFLUORMETHYLMERCAPTO)PYRIDINE

被引：11

作者：

HAAS, A

NIEMANN, U

机构：

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1978年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0022-1139(00)82464-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Methods of substituting pyridine by perhalogenomethylmercapto groups are discussed. The side chain chlorination of 2-(methylmercapto)pyridine leads gradually to 2-(trichloromethylmercapto)pyridine hydrochloride (1a) and 2-(trichloromethylmercapto)pyridine (1b). Neither a direct reaction of pyridine with CF3SCl nor the way over a Grignard reaction or a sulfenylcarboxylate lead to CF3S-substituted products. Reactions of pyridine and bromopyridines with Hg(SCF3)2 yield 1:1-adducts (2a-d) only. Lithium tetrakis(1,2-dihydro-1-pyridyl)aluminate (LDPA) reacts with CF3SCl to give 3-(trifluoromethylmercapto)pyridine (3); in addition a disubstituted product can be identified massspectroscopically. 1H- and 19F-NMR-spectra are reported. © 1978.

引用

页码：509 / 518

页数：10

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