CIRCULATING IMMUNE-COMPLEXES IN SYSTEMIC NECROTIZING VASCULITIS OF THE POLYARTERITIS-NODOSA GROUP - COMPARISON OF HBV-RELATED POLYARTERITIS-NODOSA AND CHURG STRAUSS ANGIITIS

被引：28

作者：

GUILLEVIN, L ^{[1
]}

RONCO, P ^{[1
]}

VERROUST, P ^{[1
]}

机构：

[1] HOP TENON,F-75970 PARIS 20,FRANCE

来源：

JOURNAL OF AUTOIMMUNITY | 1990年 / 3卷 / 06期

关键词：

D O I：

10.1016/S0896-8411(05)80044-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Levels of immune complexes (IC) were measured before treatment in 16 patients affected with classic polyarteritis nodosa (PN) or Churg Strauss Angiitis (CSA). The six patients with PN were positive for HBV markers. The others presented severe asthma. IgG containing immune complexes were measured using Raji cell assay. Normal level was 4,642±509 (X±SEM). IC levels were significantly different in patients with and without HBV markers. When HBV was present, mean IC level was 7,185±2,472. In the absence of HBV markers, mean IC level was 26,462±10,796. These results confirm that systemic, vasculitis is an heterogeneous group of diseases and further suggest that pathogenesis of vasculitis is different in patients with, asthma and those with HBV markers. © 1990 Academic Press Limited.

引用

页码：789 / 792

页数：4

共 11 条

[1]

SPECTRUM OF VASCULITIS - CLINICAL, PATHOLOGIC, IMMUNOLOGICAL, AND THERAPEUTIC CONSIDERATIONS [J].