THE COMPRESSIVE TO TENSILE-STRENGTH RATIO OF PHARMACEUTICAL COMPACTS

被引：14

作者：

NEWTON, JM

ALDERBORN, G

NYSTROM, C

STANLEY, P

机构：

[1] UNIV UPPSALA,DEPT PHARMACEUT,S-75123 UPPSALA,SWEDEN

[2] UNIV MANCHESTER,DEPT ENGN,MANCHESTER M13 9PL,LANCS,ENGLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 93卷 / 1-3期

关键词：

COMPACT STRENGTH; COMPRESSIVE STRENGTH; TENSILE STRENGTH; POWDER CHARACTERIZATION;

D O I：

10.1016/0378-5173(93)90185-I

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The tensile and compressive strength of cylindrical compacts of lactose and microcrystalline cellulose has been assessed by diametral compression and axial loading, respectively. The ratio of the compressive to the tensile strength of the specimens indicates that lactose is more brittle in character than microcystalline cellulose. Thus, the test procedure provides a method of characterising the mechanical properties of the powders.

引用

页码：249 / 251

页数：3

共 10 条

[1]

BASSAM F, 1988, J PHARM PHARMACOL, V40, pP68

[2]

Church M.a.K., 1983, J PHARM PHARMACOL, V50S, p43P

[3] FLEXURE TEST FOR DETERMINATION OF TABLET TENSILE-STRENGTH [J].