CORRELATES OF BONE-MINERAL DENSITY IN ELDERLY PATIENTS WITH HIP-FRACTURES

被引：8

作者：

DIRSCHL, DR

HENDERSON, RC

OAKLEY, WS

机构：

[1] UNIV N CAROLINA,SCH MED,DEPT ORTHOPAED SURG,CHAPEL HILL,NC 27514

[2] MOORE REG HOSP,PINEHURST,NC

来源：

JOURNAL OF ORTHOPAEDIC TRAUMA | 1995年 / 9卷 / 06期

关键词：

HIP FRACTURE; BONE MINERAL DENSITY; CALCIUM INTAKE; VITAMIN-D;

D O I：

10.1097/00005131-199509060-00003

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Ninety-seven elderly patients with acute fractures of the proximal femur sustained as a result of minimal trauma were studied with regard to variables that may potentially influence the incidence or outcome of fractures of the proximal femur. The mean bone mineral density (BMD) measured at the femoral neck was similar to 2 SDs below age- and sex-adjusted normals. There was a preferential loss of bone mineral from the femoral neck in younger patients with hip fractures (Z score -3.10 +/- 0.23) (mean +/- SEM) compared with the lumbar spine (Z score -1.71 +/- 0.41). Mean daily calcium intake was well below the recommended levels and calcium intake < 400 mg/day was associated with lower lumbar spine BMD Z scores (p = 0.01). Ambulatory ability was unassociated with BMD Z scores. The results of this study suggest that the femoral neck is a site of preferential bone loss in younger postmenopausal patients, and screening of patients at risk of hip fracture should measure BMD at this site. Calcium supplementation may play a role in decreasing the incidence of hip fractures.

引用

页码：470 / 475

页数：6

共 42 条

[1] Ahmad L.A., Eckhoff D.G., Kramer A.M., Outcome studies of hip fractures: A functional viewpoint, Orthop Rev, 23, pp. 19-24, (1994)
[2] Aloia J.F., Cohn S.H., Ostuni J.A., Cane R., Ellis K., Prevention of involutional bone loss by exercise, Ann Intern Med, 89, pp. 356-358, (1978)
[3] Aloia J.F., McGowan D., Evens E., Miele G., Hip fracture patients have generalized osteoporosis with a preferential deficit in the femur, Osteoporosis Int, 2, pp. 88-93, (1992)
[4] Blumenthal J.A., Emery C.F., Madden D.J., Schienbolk S., Effects of exercise training on bone density in older men and women, J am Geriatr Soc, 39, pp. 1065-1070, (1991)
[5] Chapuy M.C., Arlot M.E., Duboeuf F., Brun J., Vitamin D3 and calcium to prevent hip fractures in elderly women, N Engl J Med, 327, pp. 1637-1642, (1992)
[6] Chevalley T., Rizzoli R., Nydegger V., Slosnon D., Preferential Low BMD of the Femoral Neck in Patients With a Recent Fracture of the Proximal Femur, Osteoporosis Int, 1, pp. 147-154, (1991)
[7] Chevy S., Suominen H., Rantanen T., Parkatti T., Bone Mineral Density and Physical Activity in 50-60 Year-Old Women, Bone and Min, 12, pp. 123-132, (1991)
[8] Chrischilles E., Shireman T., Wallace R., Costs and Health Effects of osteoporotic fractures, Bone, 15, pp. 377-386, (1994)
[9] Cox M.A., Bowie R., Horne G., Hip fractures: An increasing health care cost, J Orthop Trauma, 7, pp. 52-57, (1993)
[10] Dawson-Hughes B., Dallal G.E., Krall E.A., Harris S., Effect of vitamin D supplementation on wintertime and overall bone loss in healthy post-menopausal women, Ann Intern Med, 115, pp. 505-512, (1991)

← 1 2 3 4 5 →