THE ISOLATION OF 2,2'-BIINDOLINE-3,3'-DIONES FROM INJURED FRUIT BODIES OF COLLYBIA-PERONATA AND TRICHOLOMA-SCALPTURATUM

Several 3-indolinone dimers have been isolated from EtOAc extracts of the fruit bodies of Collybia peronata {peronatin A [1] and peronatin B [2]} and Tricholoma scalpturatum {7-hydroxy-7'-methoxyperonatin B [3] and 7,7'-dimethoxyperonatin B [4]}, and their structures have been determined by mass spectrometry and nmr spectroscopy. The compounds are formed in the fruit bodies as a response to injury, although small amounts may be present also in intact specimens. It is suggested that they are probably formed by oxidative coupling of the corresponding 3-indolinones.