METABOLIC FORMATION OF 1,9,10-TRIHYDROXY-9,10-DIHYDRO-3-METHYLCHOLANTHRENE - POTENTIAL PROXIMATE CARCINOGEN FROM 3-METHYLCHOLANTHRENE

被引：76

作者：

THAKKER, DR

LEVIN, W

WOOD, AW

CONNEY, AH

STOMING, TA

JERINA, DM

机构：

[1] NIAMDD,CHEM LAB,OXIDAT MECH SECT,BETHESDA,MD 20014

[2] HOFFMANN LA ROCHE INC,DEPT BIOCHEM & DRUG METAB,NUTLEY,NJ 07110

[3] MED COLL GEORGIA,DEPT CELL & MOLEC BIOL,AUGUSTA,GA 30902

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1978年 / 100卷 / 02期

关键词：

D O I：

10.1021/ja00470a057

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：645 / 647

页数：3

共 25 条

[1]

FIESER LF, 1935, J AM CHEM SOC, V57, P592

[2] OXIDATION OF CARCINOGENS BENZO[A]PYRENE AND BENZO[A]ANTHRACENE TO DIHYDRODIOLS BY A BACTERIUM [J].

GIBSON, DT ;

MAHADEVAN, V ;

JERINA, DM ;

YAGI, H ;

YEH, HJC .

SCIENCE, 1975, 189 (4199) :295-297

[3]

IBALL JOHN, 1939, AMER JOUR CANCER, V35, P188

[4]

Jerina D.M., 1977, ORIGINS HUMAN CANCER, P639

[5] DIHYDRODIOLS FROM ANTHRACENE AND PHENANTHRENE [J].

JERINA, DM ;

SELANDER, H ;

YAGI, H ;

WELLS, MC ;

DAVEY, JF ;

MAHADEVAN, V ;

GIBSON, DT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (19) :5988-5996

[6] ARENE OXIDES - NEW ASPECT OF DRUG-METABOLISM [J].

JERINA, DM ;

DALY, JW .

SCIENCE, 1974, 185 (4151) :573-582

[7]

JERINA DM, 1976, IN VITRO METABOLIC A, P179

[8]

JERINA DM, 1976, DRUG METABOLISM MICR, P13

[9] BENZO[A]PYRENE 7,8-DIHYDRODIOL IS MORE CARCINOGENIC THAN BENZO[A]PYRENE IN NEWBORN MICE [J].

KAPITULNIK, J ;

LEVIN, W ;

CONNEY, AH ;

YAGI, H ;

JERINA, DM .

NATURE, 1977, 266 (5600) :378-380

[10]

KARLE JM, 1977, TETRAHEDRON LETT, P4021

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