STRETCH-ACTIVATED CATION CHANNELS WITH LARGE UNITARY CONDUCTANCE IN LEECH CENTRAL NEURONS

被引：19

作者：

PELLEGRINO, M

PELLEGRINI, M

SIMONI, A

GARGINI, C

机构：

[1] Dipartimento di Fisiologia, Biochimica Universitá di Pisa, Pisa

来源：

BRAIN RESEARCH | 1990年 / 525卷 / 02期

关键词：

Leech; Osmoregulation; Single channel; Stretch-activated;

D O I：

10.1016/0006-8993(90)90883-D

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Stretch-activated cation channels were identified in the soma membrane of leech central neurons. These channels were almost silent under normal experimental conditions and were distinctly activated by application of negative pressure to the patch pipette. The channels exhibited a preferential selectivity for K+ and a slope conductance of about 200 pS, in symmetrical K+ solution. In cell-attached patches these cation channels were activated by cell swelling. © 1990.

引用

页码：322 / 326

页数：5

共 25 条

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