ACUTE BARIUM POISONING WITH RESPIRATORY-FAILURE AND RHABDOMYOLYSIS

被引:52
作者
JOHNSON, CH
VANTASSELL, VJ
机构
[1] Departments of Internal Medicine and Emergency Medicine, Maricopa Medical Center, Phoenix, AZ
关键词
barium; poisoning; rhabdomyolysis; barium poisoning;
D O I
10.1016/S0196-0644(05)81393-9
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Barium is a divalent alkaline earth metal used as the insoluble sulfate salt in contrast radiography and soluble acid salts in industry. Barium poisoning results from ingestion or inhalation of the acid salts; the most common poisoning occurs after ingestion of the rodenticide barium carbonate (BaCO3). We report seven cases of BaCO3 poisoning in one family; three hospitalized patients displayed classic signs of barium toxicity, and one patient also developed rhabdomyolysis, respiratory failure, and hypophosphatemia. All patients survived. Rhabdomyolysis has not been previously reported in barium poisoning, and this is the first reported barium poisoning epidemic in the United States. The history, pathophysiology, and treatment of barium poisoning are reviewed.
引用
收藏
页码:1138 / 1142
页数:5
相关论文
共 26 条
[1]  
Casarett, Casarett and Doull's Toxicology: The Basic Science of Poisons, (1980)
[2]  
Schott, Some observations on the history of the use of barium salts in medicine, Med Hist, 18, pp. 9-21, (1974)
[3]  
Schroeder, Tipton, Nason, Trace metals in man: Strontium and barium, J Chronic Dis, 25, pp. 491-517, (1972)
[4]  
Baselt, Disposition of Toxic Drugs and Chemicals in Man, pp. 69-71, (1982)
[5]  
Machata, Barium, Handbook on Toxicity of Inorganic Compounds, pp. 97-101, (1987)
[6]  
Roza, Berman, The pathophysiology of barium: Hypokalemic and cardiovascular effects, J Pharmacol Exp Ther, 177, pp. 433-439, (1971)
[7]  
Gosselin, Smith, Hodge, Et al., Clinical Toxicology of Commercial Products, pp. 11161-11163, (1984)
[8]  
Schott, McArdle, Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis, J Neurol Neurosurg Psychiatr, 37, pp. 32-39, (1974)
[9]  
Volle, Blockade by barium of potassium fluxes in frog sartorius muscle, Life Sci, 9, pp. 175-180, (1970)
[10]  
Layzer, Periodic paralysis and the sodium-potassium pump, Ann Neurol, 11, pp. 547-552, (1982)