ASSIGNMENT OF A GENE FOR HUMAN QUINOID-DIHYDROPTERIDINE REDUCTASE (QDPR, EC 1.6.5.1) TO CHROMOSOME-4

被引：18

作者：

KUHL, P

OLEK, K

WARDENBACH, P

GRZESCHIK, KH

机构：

[1] UNIV MUNSTER,INST HUMAN GENET,D-4400 MUNSTER,FED REP GER

[2] UNIV BONN,INST HUMAN GENET,D-5300 BONN 1,FED REP GER

来源：

HUMAN GENETICS | 1979年 / 53卷 / 01期

关键词：

D O I：

10.1007/BF00289450

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An acrylamide gel electrophoretic procedure is described which allows the separation of human quinoid-dihydropteridine reductase (QDPR), EC 1.6.5.1) from the homologous enzyme expressed in established rodent cell lines. The human enzyme marker segregates exclusively with chromosome 4 in a series of well characterized man-mouse somatic cell hybrid clones from our clone bank. This observation supports the assignment of a structural gene for QDPR to human chromosome 4. © 1979 Springer-Verlag.

引用

页码：47 / 49

页数：3

共 12 条

[1] NAPHTHOQUINONE ADSORBENT FOR AFFINITY CHROMATOGRAPHY OF HUMAN DIHYDROPTERIDINE REDUCTASE [J].