NATURE OF THE GENETIC DETERMINANT FOR THE SHV-1 BETA-LACTAMASE

被引：60

作者：

NUGENT, ME

HEDGES, RW

机构：

[1] Department of Bacteriology, Royal Postgraduate Medical School, London

来源：

MOLECULAR AND GENERAL GENETICS | 1979年 / 175卷 / 03期

关键词：

D O I：

10.1007/BF00397222

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In two unrelated plasmids of incompatibility groups FII and N the gene for the SHV-1 β-lactamase exists as part of a transposable element of molecular weight 9.5 megadaltons. This transposon has moved onto plasmids of at least three incompatibility groups; PI, Iα and J. This confirms the suggestion that the recent spread of the SHV-1 β-lactamase has been associated with the transposition of the genetic determinant of this enzyme between unrelated plasmids. © 1979 Springer-Verlag.

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页码：239 / 243

页数：5

相关论文

共 22 条

[1] ASSAY OF DEOXYRIBONUCLEIC-ACID HOMOLOGY USING A SINGLE-STRAND-SPECIFIC NUCLEASE AT 75 C [J].

BARTH, PT ;

GRINTER, NJ .

JOURNAL OF BACTERIOLOGY, 1975, 121 (02) :434-441

[2] R FACTORS FROM PROTEUS-RETTGERI [J].

COETZEE, JN ;

DATTA, N ;

HEDGES, RW .

JOURNAL OF GENERAL MICROBIOLOGY, 1972, 72 (OCT) :543-+

[3] PROPERTIES OF AN R-FACTOR FROM PSEUDOMONAS-AERUGINOSA [J].

DATTA, N ;

HEDGES, RW ;

SHAW, EJ ;

SYKES, RB ;

RICHMOND, MH .

JOURNAL OF BACTERIOLOGY, 1971, 108 (03) :1244-+

[4]

DATTA N, PLASMID

[5] RAPID METHOD FOR IDENTIFICATION OF PLASMID DEOXYRIBONUCLEIC-ACID IN BACTERIA [J].

ECKHARDT, T .

PLASMID, 1978, 1 (04) :584-588

[6] KLEBSIELLA-ENTEROBACTER-SERRATIA DIVISION - BIOCHEMICAL AND SEROLOGIC CHARACTERISTICS AND SUSCEPTIBILITY TO ANTIBIOTICS [J].

EICKHOFF, TC ;

STEINHAUER, BW ;

FINLAND, M .

ANNALS OF INTERNAL MEDICINE, 1966, 65 (06) :1163-+

[7] TRANSPOSITION OF AMPICILLIN RESISTANCE FROM RP4 TO OTHER REPLICONS [J].

HEDGES, RW ;

JACOB, AE .

MOLECULAR & GENERAL GENETICS, 1974, 132 (01) :31-40

[8] PROPERTIES OF PLASMIDS PRODUCED BY RECOMBINATION BETWEEN R-FACTORS OF GROUPS-J AND GROUPS-F2 [J].

HEDGES, RW ;

JACOB, AE ;

DATTA, N ;

COETZEE, JN .

MOLECULAR AND GENERAL GENETICS, 1975, 140 (04) :289-302

[9] PROPERTIES OF A TRANSPOSON CONFERRING RESISTANCE TO PENICILLINS AND STREPTOMYCIN [J].

HEDGES, RW ;

MATTHEW, M ;

SMITH, DI ;

CRESSWELL, JM ;

JACOB, AE .

GENE, 1977, 1 (3-4) :241-253

[10] TRANSLOCATION OF A PLASMID DNA SEQUENCE WHICH MEDIATES AMPICILLIN RESISTANCE - MOLECULAR NATURE AND SPECIFICITY OF INSERTION [J].

HEFFRON, F ;

RUBENS, C ;

FALKOW, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (09) :3623-3627