SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE ENANTIOMERS OF THE DOPAMINE AUTORECEPTOR AGONIST PD-135385

被引：11

作者：

JAEN, JC ^{[1
]}

CAPRATHE, BW ^{[1
]}

WISE, LD ^{[1
]}

MELTZER, LT ^{[1
]}

PUGSLEY, TA ^{[1
]}

HEFFNER, TG ^{[1
]}

机构：

[1] WARNER LAMBERT PARKE DAVIS,PARKE DAVIS PHARMACEUT RES DIV,DEPT PHARMACOL,ANN ARBOR,MI 48105

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 04期

关键词：

D O I：

10.1016/S0960-894X(01)81245-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：639 / 644

页数：6

共 21 条

[1] DOPAMINE AUTORECEPTORS - PHARMACOLOGICAL CHARACTERIZATION BY MICROIONTOPHORETIC SINGLE CELL RECORDING STUDIES [J].

AGHAJANIAN, GK ;

BUNNEY, BS .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1977, 297 (01) :1-7

[2] RELATIVE DOPAMINE D1 AND D2 RECEPTOR AFFINITY AND EFFICACY DETERMINE WHETHER DOPAMINE AGONISTS INDUCE HYPERACTIVITY OR ORAL STEREOTYPY IN RATS [J].

ARNT, J ;

BOGESO, KP ;

HYTTEL, J ;

MEIER, E .

PHARMACOLOGY & TOXICOLOGY, 1988, 62 (03) :121-130

[3]

CAPRATHE BW, 1990, 199TH ACS NAT M

[4] DOPAMINE RECEPTOR AGONISTS - INTRINSIC ACTIVITY VS STATE OF RECEPTOR [J].

CARLSSON, A .

JOURNAL OF NEURAL TRANSMISSION, 1983, 57 (04) :309-315

[5]

CARLSSON A, 1988, RECEPTORS LIGANDS PS, P1

[6]

CASEY DE, 1990, WESTERN J MED, V153, P535

[7]

HEFFNER T, 1992, NOVEL ANTIPSYCHOTIC

[8] DOPAMINE AUTORECEPTOR AGONISTS AS POTENTIAL ANTIPSYCHOTICS .2. (AMINOALKOXY)-4H-1-BENZOPYRAN-4-ONES [J].

JAEN, JC ;

WISE, LD ;

HEFFNER, TG ;

PUGSLEY, TA ;

MELTZER, LT .

JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (01) :248-256

[9] SYNTHESIS AND DOPAMINERGIC ACTIVITY OF THE ENANTIOMERS OF 6-METHYL-4,5,5A,6,7,8-HEXAHYDROTHIAZOLO[4,5-F]QUINOLIN-2-AMINE (PD-128483) [J].

JAEN, JC ;

CAPRATHE, BW ;

WISE, LD ;

PUGSLEY, TA ;

MELTZER, LT ;

HEFFNER, TG .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1991, 1 (10) :539-544

[10] NOVEL 4,5,6,7-TETRAHYDROBENZOTHIAZOLE DOPAMINE AGONISTS DISPLAY VERY LOW STEREOSELECTIVITY IN THEIR INTERACTION WITH DOPAMINE-RECEPTORS [J].

JAEN, JC ;

CAPRATHE, BW ;

WISE, LD ;

SMITH, SJ ;

PUGSLEY, TA ;

HEFFNER, TG ;

MELTZER, LT .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1991, 1 (04) :189-192

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