PRELIMINARY-REPORT OF UNEXPECTED LOCAL REACTIONS TO A PROGESTOGEN-RELEASING CONTRACEPTIVE VAGINAL RING

被引：47

作者：

BOUNDS, W

SZAREWSKI, A

LOWE, D

GUILLEBAUD, J

机构：

[1] IMPERIAL CANC RES FUND,DEPT MATH STAT & EPIDEMIOL,LONDON WC2A 3PX,ENGLAND

[2] ST BARTHOLOMEWS HOSP & MED COLL,DEPT HISTOPATHOL,LONDON EC1A 7BE,ENGLAND

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1993年 / 48卷 / 02期

关键词：

PROGESTOGEN; CONTRACEPTIVE; VAGINAL RING; LOCAL REACTIONS;

D O I：

10.1016/0028-2243(93)90252-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This is the first report of vaginal erythematous areas associated with the use of a levonorgestrel-releasing contraceptive ring. Of 139 female subjects, 48 developed lesions of varying size and degrees of redness. Sixteen of these have undergone serial colposcopy and thirteen have also had biopsy examinations, which revealed acetowhite areas and, histologically, chronic inflammation with widely dilated vessels and frequently with thinning of the epithelium. The cause remains uncertain but hormonal, chemical and physical effects might all have a role.

引用

页码：123 / 125

页数：3