INFECTION OF MONOCYTES MACROPHAGES BY HIV INVITRO

被引：37

作者：

VONBRIESEN, H

ANDREESEN, R

ESSER, R

BRUGGER, W

MEICHSNER, C

BECKER, K

RUBSAMENWAIGMANN, H

机构：

[1] HOECHST AG,W-6230 FRANKFURT 80,GERMANY

[2] UNIV FREIBURG,MED KLIN,W-7800 FREIBURG,GERMANY

来源：

RESEARCH IN VIROLOGY | 1990年 / 141卷 / 02期

关键词：

HIV; Monocyte; Macrophage; Lymphocyte; In vitro infection;

D O I：

10.1016/0923-2516(90)90025-E

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Because of the very important role of the mononuclear phagocyte system in the immunopathogenesis of HIV infection, a culture system for in vitro studies of infection of monocytes/macrophages with HIV was developed. A method is described for the infection of human monocytes/macrophages cultured on hydrophobic membranes (Teflon) with different strains of HIV. The HIV isolates can be characterized according to their replication potential on monocyte/macrophages cultures. The biological properties of some HIV1 and HIV2 isolates are compared in lymphocyte and monocyte/macrophage cultures. © 1990.

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页码：225 / 231

页数：7

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