IGA NEPHRITIS - ON THE IMPORTANCE OF MORPHOLOGICAL AND CLINICAL-PARAMETERS IN THE LONG-TERM PROGNOSIS OF 239 PATIENTS

被引：134

作者：

BOGENSCHUTZ, O ^{[1
]}

BOHLE, A ^{[1
]}

BATZ, C ^{[1
]}

WEHRMANN, M ^{[1
]}

PRESSLER, H ^{[1
]}

KENDZIORRA, H ^{[1
]}

GARTNER, HV ^{[1
]}

机构：

[1] UNIV TUBINGEN, INST PATHOL, LIEBERMEISTERSTR 8, W-7400 TUBINGEN 1, GERMANY

来源：

AMERICAN JOURNAL OF NEPHROLOGY | 1990年 / 10卷 / 02期

关键词：

IgA nephritis; Interstitial fibrosis; Long-term prognosis; Tubulointerstitial lesions;

D O I：

10.1159/000168068

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

This study is concerned with the correlation between tubulointerstitial changes (interstitial fibrosis, acuterenal failure, and interstitial fibrosis with acute renal failure), glomerular changes (focal and segmental lesions, hyperperfusion lesions), vascular changes, clinical data at the time of biopsy (serum creatinine concentration, creatinine clearance, hematuria, proteinuria, and hypertension) and first symptoms (hematuria, proteinuria and hypertension) and the kidney survival rate in 239 patients with IgA nephritis without nephrotic syndrome. The morphological and clinical parameters were subjected to multivariate analysis in order to examine their significance with regard to the prognosis. The interstitial fibrosis was proven to be the most important morphological parameter, and the most important clinical parameters were the serum creatinine concentration and the creatinine clearance. © 1990 S. Karger AG, Basel.

引用

页码：137 / 147

页数：11

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