ERYTHROCYTE GLUCOSE-6-PHOSPHATE-DEHYDROGENASE (1.1.1.49) DEFICIENCY IN ANTALYA PROVINCE, TURKEY - AN EPIDEMIOLOGIC AND BIOCHEMICAL-STUDY

被引：15

作者：

AKSU, TA ^{[1
]}

ESEN, F ^{[1
]}

DOLUNAY, MS ^{[1
]}

ALICIGUZEL, Y ^{[1
]}

YUCEL, G ^{[1
]}

CALI, S ^{[1
]}

BAYKAL, Y ^{[1
]}

机构：

[1] AKDENIZ UNIV,SCH MED,DEPT BIOCHEM,07059 ANTALYA,TURKEY

来源：

AMERICAN JOURNAL OF EPIDEMIOLOGY | 1990年 / 131卷 / 06期

关键词：

Enzymes; Glucosephosphate dehydrogenase; Glucosephosphate dehydrogenase deficiency;

D O I：

10.1093/oxfordjournals.aje.a115602

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Glucose-6-phosphate dehydrogenase (1.1.1.49) activity was assessed in 1986-1988 in blood samples from 1,521 individuals from 375 families living in Antalya city and adjacent villages by Beutler's fluorescence spot test The families were randomly selected by the State Statistical Institute. Complete deficiency occurred in 7.4% of males and 1.8% of females. Mean enzyme activity was 6.77 ± 1.07 IU/g Hb in normals and ranged between 0 and 0.48 IU/g Hb in those considered deficient Kinetic measurements made with partially purified enzyme showed that GdB+ and GdB- variants were present in normal and in deficient subjects, respectively. © 1990 by the Johns Hopkins University School of Hygiene and Public Health.

引用

页码：1094 / 1097

页数：4

共 14 条

[1] 3 NEW G6PD VARIANTS, G6PD ADANA, G6PD SAMANDAG, AND G6PD BALCALI IN CUKUROVA, TURKEY [J].