ESTABLISHMENT OF THEILERIA-INFECTED BOVINE CELL-LINES IN SCID MICE

被引：34

作者：

FELL, AH

PRESTON, PM

ANSELL, JD

机构：

[1] Department of Zoology, University of Edinburgh, Edinburgh

来源：

PARASITE IMMUNOLOGY | 1990年 / 12卷 / 03期

基金：

英国惠康基金;

关键词：

scid mice; Theileria‐infected bovine cells;

D O I：

10.1111/j.1365-3024.1990.tb00959.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Summary Bovine cells tranformed by infection with the protozoan parasite Theileria annulata were inoculated subcutaneously or intraperitoneally into C.B.‐17 scid mice. Mice injected subcutaneously developed solid tumours at the injection site, whilst those injected intraperitoneally developed ascites. Schizont‐infected cells were found in other tissues: infected cells spread much more easily from the intraperitoneal site. Karyotyping of cells isolated from tumours showed no evidence of transfer of parasites to murine cells. These results show that the scid mouse can be used as a host for Theileria‐infected bovine cells. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：335 / 339

页数：5

共 10 条

[1]

BOSMA M, 1988, CURR TOP MICROBIOL, V137, P197

[2]

BROWN CDEG, 1983, INVITRO CULTIVATION, P312

[3]

DRURY RAB, 1980, CARLETONS HISTOLOGIC, P216

[4]

FELL AH, 1988, T ROY SOC TROP MED H, V82, P941

[5] IMMUNIZATION AGAINST BOVINE TROPICAL THEILERIASIS (THEILERIA-ANNULATTA INFECTION) [J].

GILL, BS ;

BHATTACHARYULU, Y ;

KAUR, D .

RESEARCH IN VETERINARY SCIENCE, 1976, 21 (02) :146-149

[6] ESTABLISHMENT OF THEILERIA-PARVA-INFECTED BOVINE TISSUE-CULTURE IN SWISS AND ATHYMIC (NUDE) MICE [J].

IRVIN, AD ;

BROWN, CGD ;

KANHAI, GK ;

STAGG, DA .

VETERINARY PARASITOLOGY, 1977, 3 (02) :141-160

[7] THE SCID-HU MOUSE - MURINE MODEL FOR THE ANALYSIS OF HUMAN HEMATOLYMPHOID DIFFERENTIATION AND FUNCTION [J].

MCCUNE, JM ;

NAMIKAWA, R ;

KANESHIMA, H ;

SHULTZ, LD ;

LIEBERMAN, M ;

WEISSMAN, IL .

SCIENCE, 1988, 241 (4873) :1632-1639

[8] TRANSFER OF A FUNCTIONAL HUMAN IMMUNE-SYSTEM TO MICE WITH SEVERE COMBINED IMMUNODEFICIENCY [J].

MOSIER, DE ;

GULIZIA, RJ ;

BAIRD, SM ;

WILSON, DB .

NATURE, 1988, 335 (6187) :256-259

[9] INFECTION OF THE SCID-HU MOUSE BY HIV-1 [J].

NAMIKAWA, R ;

KANESHIMA, H ;

LIEBERMAN, M ;

WEISSMAN, IL ;

MCCUNE, JM .

SCIENCE, 1988, 242 (4886) :1684-1686

[10]

Pipano E., 1981, Advances in the Control of Theileriosis. Proceedings of an International Conference held at the International Laboratory for Research on Animal Diseases in Nairobi, 9-13th February, 1981, P242

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