ENDOCRINE PANCREAS - 3-DIMENSIONAL RECONSTRUCTION SHOWS 2 TYPES OF ISLETS OF LANGERHANS

被引：228

作者：

BAETENS, D

MALAISSELAGAE, F

PERRELET, A

ORCI, L

机构：

[1] Institute of Histology and Embryology, University of Geneva Medical School

来源：

SCIENCE | 1979年 / 206卷 / 4424期

关键词：

D O I：

10.1126/science.390711

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Three-dimensional reconstructions of islets of Langerhans, based on immunofluorescent staining of successive serial sections with antiserums to insulin, glucagon, somatostatin, and pancreatic polypeptide reveal a marked difference in the number of cells containing glucagon and pancreatic polypeptide depending on the anatomical location of the islet in the pancreas. The two types of islets are situated in regions of exocrine tissue that are drained by different excretory ducts. This demonstration contradicts the assumption that all islets in the pancreas are similar in their endocrine cell content. Copyright © 1979 AAAS.

引用

页码：1323 / 1325

页数：3

共 18 条

[1]

BAETENS D, 1978, DIABETES, V27, P1, DOI 10.2337/diabetes.27.1.1

[2]

BEVELANDER G, 1979, ESSENTIALS HISTOLOGY

[3]

CAHN JW, 1959, T AM I MIN MET ENG, V215, P526

[4] STUDIES ON ANTIBODY PRODUCTION .1. A METHOD FOR THE HISTOCHEMICAL DEMONSTRATION OF SPECIFIC ANTIBODY AND ITS APPLICATION TO A STUDY OF THE HYPERIMMUNE RABBIT [J].