SYNTHESIS AND CHARACTERIZATION OF HIGHLY STABLE POLYMER-COATED AMINOSILICA PACKING MATERIAL FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：15

作者：

KUTSUNA, H

OHTSU, Y

YAMAGUCHI, M

机构：

[1] Basic Research Laboratories, R and D Headquarters, Shiseido Co., Ltd., Kohoku-ku, Yokohama, 223

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 635卷 / 02期

关键词：

D O I：

10.1016/0021-9673(93)80360-K

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A synthetic procedure leading to an amino-bonded stationary phase for high-performance liquid chromatography was developed. The silica surface was first coated with a silicone polymer monolayer and an amino functionality was subsequently attached to the polymer layer. The polymer-coated amino-bonded phase showed improved stability and separation in the analysis of carbohydrates and nucleotides over conventional aminopropylsilylated silicas.

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页码：187 / 193

页数：7

相关论文

共 16 条

[1] PRACTICAL ASPECTS OF NORMAL-PHASE CHROMATOGRAPHY [J].

ABBOTT, SR .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1980, 18 (10) :540-550

[2] CHEMICALLY BONDED STATIONARY PHASES FOR AQUEOUS HIGH-PERFORMANCE EXCLUSION CHROMATOGRAPHY [J].

ENGELHARDT, H ;

MATHES, D .

JOURNAL OF CHROMATOGRAPHY, 1977, 142 (NOV) :311-320

[3]

FUKUI H, 1990, CONTROLLED INTERPHASES IN COMPOSITE MATERIALS, P469

[4] SYNTHESIS AND CHARACTERIZATION OF HIGHLY STABLE BONDED PHASES FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY COLUMN PACKINGS [J].

KIRKLAND, JJ ;

GLAJCH, JL ;

FARLEE, RD .

ANALYTICAL CHEMISTRY, 1989, 61 (01) :2-11

[5] RECENT ADVANCES IN HPLC PACKINGS AND COLUMNS [J].

MAJORS, RE .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1980, 18 (10) :488-511

[6] PERFORMANCE OF POLYMER-COATED SILICA C-18 PACKING MATERIALS PREPARED FROM HIGH-PURITY SILICA-GEL - THE SUPPRESSION OF UNDESIRABLE SECONDARY RETENTION PROCESSES [J].

OHTSU, Y ;

SHIOJIMA, Y ;

OKUMURA, T ;

KOYAMA, J ;

NAKAMURA, K ;

NAKATA, O ;

KIMATA, K ;

TANAKA, N .

JOURNAL OF CHROMATOGRAPHY, 1989, 481 :147-157

[7] STRUCTURES AND CHROMATOGRAPHIC CHARACTERISTICS OF CAPSULE-TYPE SILICA-GELS COATED WITH HYDROPHOBIC POLYMERS IN REVERSED-PHASE LIQUID-CHROMATOGRAPHY [J].

OHTSU, Y ;

FUKUI, H ;

KANDA, T ;

NAKAMURA, K ;

NAKANO, M ;

NAKATA, O ;

FUJIYAMA, Y .

CHROMATOGRAPHIA, 1987, 24 :380-384

[8] APPLICATION OF A NEW CAPSULE-TYPE SILICA-GEL COATED WITH HYDROPHOBIC POLYMER TO PREPARATIVE LIQUID-CHROMATOGRAPHY ON AN INDUSTRIAL-SCALE [J].

OHTSU, Y ;

SHIROTA, O ;

OGAWA, T ;

TANAKA, I ;

OHTA, T ;

NAKATA, O ;

FUJIYAMA, Y .

CHROMATOGRAPHIA, 1987, 24 :351-356

[9] CHARACTERIZATION OF POLYMERIC AMINOPROPYL DERIVATIZED SILICA SUPPORT FOR THE SIZE-EXCLUSION CHROMATOGRAPHY OF CATIONIC POLYMERS [J].

PATTON, EV ;

WONNACOTT, DM .

JOURNAL OF CHROMATOGRAPHY, 1987, 389 (01) :115-125

[10] CHROMATOGRAPHIC STABILITY OF SILICA-BASED AMINOPROPYL-BONDED STATIONARY PHASES [J].

PORSCH, B ;

KRATKA, J .

JOURNAL OF CHROMATOGRAPHY, 1991, 543 (01) :1-7