STEREOSELECTIVE ACYL TRANSFER-REACTIONS CONTROLLED BY THE DIPHENYLPHOSPHINOYL GROUP - X-RAY STRUCTURES OF STABLE CRYSTALLINE SILYLATED TETRAHEDRAL INTERMEDIATES

被引：16

作者：

FEEDER, N ^{[1
]}

HUTTON, G ^{[1
]}

WARREN, S ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)78217-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acyl transfer with LDA on benzoates of single diastereoisomers of 3-hydroxyalkyldiphenylphosphine oxides in the presence of trimethylsilyl chloride gives silylated tetrahedral intermediates in carbonyl displacement reactions with the stereochemically controlled creation of two new chiral centres. X-rays reveal the stereochemistry.

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收藏

页码：5911 / 5914

页数：4

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