PURE RED-CELL APLASIA FOLLOWING ABO MISMATCHED MARROW TRANSPLANTATION FOR CHRONIC LYMPHOCYTIC-LEUKEMIA - RESPONSE TO ANTITHYMOCYTE GLOBULIN

被引:20
作者
BIERMAN, PJ
WARKENTIN, P
HUTCHINS, MR
KLASSEN, LW
机构
[1] Departments of Internal Medicine, University of Nebraska Medical Center, Omaha
[2] Departments of Pathology/Microbiology, University of Nebraska Medical Center, Omaha
[3] Departments of Wedgewood, Medical Center, Lincoln, NE
关键词
BONE MARROW TRANSPLANTATION; ABO MISMATCHED MARROW TRANSPLANTATION; RED BLOOD CELL APLASIA; ANTITHYMOCYTE GLOBULIN; CHRONIC LYMPHOCYTIC LEUKEMIA;
D O I
10.3109/10428199309148522
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Pure red cell aplasia was observed in a 28 year old woman following a major ABO mismatched allogeneic bone marrow transplant for chronic lymphocytic leukemia. No evidence of red blood cell production was observed for more than one year following transplant despite the absence of high isohemagglutinin titers. Treatment with antithymocyte globulin resulted in prompt restoration of reticulocytosis. Therapy with antithymocyte globulin should be considered in these instances when red cell aplasia follows mismatched allogeneic marrow transplantation.
引用
收藏
页码:169 / 171
页数:3
相关论文
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