DISTRIBUTION OF PUTATIVE ODOR RECEPTOR PROTEINS IN OLFACTORY EPITHELIUM

被引：31

作者：

KOSHIMOTO, H ^{[1
]}

KATOH, K ^{[1
]}

YOSHIHARA, Y ^{[1
]}

MORI, K ^{[1
]}

机构：

[1] OSAKA BIOSCI INST,DEPT NEUROSCI,6-2-4 FURUEDAI,SUITA,OSAKA 565,JAPAN

来源：

NEUROREPORT | 1992年 / 3卷 / 06期

关键词：

ODOR RECEPTOR PROTEIN; OLFACTORY CILIA; OLFACTORY EPITHELIUM; SPATIAL LOCALIZATION;

D O I：

10.1097/00001756-199206000-00017

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

To investigate immunohistochemically the spatial localization of putative odour receptor proteins, we synthesized a polypeptide which corresponds to a region of a putative odour receptor protein, I3, and raised an antibody to the peptide. In rat olfactory epithelium, the antibody specifically recognized cilia of a small subset of olfactory receptor neurons, suggesting that the odour receptor protein is localized selectively in the cilia. Olfactory receptor neurons having immunoreactive cilia were distributed sparsely throughout the epithelium. This suggests that receptor neurons expressing a similar odour receptor protein are probably distributed similarly in the epithelium.

引用

页码：521 / 523

页数：3

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