INHIBITION OF CHOLESTEROL-SYNTHESIS INVITRO AND INVIVO BY ML-236A AND ML-236B, COMPETITIVE INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE

被引：241

作者：

ENDO, A ^{[1
]}

TSUJITA, Y ^{[1
]}

KURODA, M ^{[1
]}

TANZAWA, K ^{[1
]}

机构：

[1] SANKYO CO LTD,FERMENTAT RES LABS,SHINAGAWA KU,TOKYO 140,JAPAN

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1977年 / 77卷 / 01期

关键词：

D O I：

10.1111/j.1432-1033.1977.tb11637.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

引用

页码：31 / 36

页数：6

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[5]

COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY [J].

ENDO, A ;

KURODA, M ;

TANZAWA, K .

FEBS LETTERS, 1976, 72 (02) :323-326

[6]

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ENDO, A ;

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TSUJITA, Y .

JOURNAL OF ANTIBIOTICS, 1976, 29 (12) :1346-1348

[7]

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[8]

KURODA M, 1977, BIOCHIM BIOPHYS ACTA, V486, P70

[9]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[10]

Rodwell V W, 1976, Adv Lipid Res, V14, P1

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