Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006. This opinion addresses the scientific substantiation of health claims in relation to vitamin D and normal absorption of calcium; protein and growth or maintenance of muscle mass; protein and maintenance of normal bone; calcium and maintenance of normal bone; plant stanols and maintenance of normal blood cholesterol concentrations; alpha-linolenic acid (ALA) and maintenance of normal blood cholesterol concentrations; replacement of mixtures of saturated fatty acids (SFAs) as present in foods or diets with mixtures of polyunsaturated fatty acids (PUFAs) and maintenance of normal blood LDL-cholesterol concentrations; lactase and breaking down lactose; ethanol-water extract of Caralluma fimbriata and reduction in waist circumference; ethanol-water extract of Caralluma fimbriata and reduction of body weight; ethanol-water extract of Caralluma fimbriata and reduction of appetite; pectins and maintenance of normal blood cholesterol concentrations; chromium and maintenance of normal blood glucose concentrations; choline and maintenance of normal liver function. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13 health claims and references that EFSA has received from Member States or directly from stakeholders. The Panel concludes that the following health claims have already been assessed with a favourable outcome: Vitamin D and normal absorption of calcium (ID 215). Protein and growth or maintenance of muscle mass (ID 1398). Protein and maintenance of normal bone (ID 4704). Calcium and maintenance of normal bone (ID 4704). Plant stanols and maintenance of normal blood cholesterol concentrations (ID 568). Alpha-linolenic acid (ALA) and maintenance of normal blood cholesterol concentrations (ID 568). Replacement of mixtures of saturated fatty acids (SFAs) as present in foods or diets with mixtures of polyunsaturated fatty acids (PUFAs) and maintenance of normal blood LDLcholesterol concentrations (ID 674, 4335). Lactase and breaking down lactose (ID 1974). Pectins and maintenance of normal blood cholesterol concentrations (ID 4236). Chromium and maintenance of normal blood glucose concentrations (ID 4698). Choline and maintenance of normal liver function (ID 712, 1633). The Panel concludes that the following health claims have already been assessed with an unfavourable outcome and that the references cited did not provide any additional scientific data which could be used to substantiate the claims: Ethanol-water extract of Caralluma fimbriata and reduction in waist circumference (ID 4191). Ethanol-water extract of Caralluma fimbriata and reduction of body weight (ID 4192). Ethanol-water extract of Caralluma fimbriata and reduction of appetite (ID 4193).