INTERPRETATION OF ISOLATED AGENESIS OF THE PITUITARY

被引：26

作者：

ROUX, C

DUPUIS, R

HORVATH, C

GIROUD, A

机构：

[1] Laboratoire d'Embryologie, Faculté de Médecine Saint-Antoine, Paris, 75571, 27, rue Chaligny

来源：

TERATOLOGY | 1979年 / 19卷 / 01期

关键词：

D O I：

10.1002/tera.1420190107

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cholesterol synthesis inhibitors administered to rats caused more or less complete forms of the holoprosencéphalic syndrome, consisting of severe abnormalities of the brain, sense organs and pituitary. The absence of the pituitary was also observed in fetuses without externally visible cephalic abnormalities. These observations suggest that the isolated absence of the pituitary is the lesser form of the holoprosencephalic syndrome. This interpretation is also valid for cases of isolated absence of the pituitary observed in humans. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：39 / 43

页数：5

共 17 条

[1] Experimental studies on the development of the eye II the eye-forming potencies of the median portions of the urodelan neural plate (triton teniatus and amblystoma punctatum) [J].