INVITRO ACTIONS OF SOME ANTIBIOTICS ON PHOSPHOLIPASES

被引：8

作者：

SUGATANI, J

SAITO, K

HONJO, I

机构：

[1] Kansai Medical University, Moriguchi

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 07期

关键词：

D O I：

10.7164/antibiotics.32.734

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The effects of some antibiotics on activities of phospholipase A2, B and C were investigated in vitro. Tetracyclines, macrolides, chloramphenicol and carbenicillin inhibited the activity of Crotalus adamanteus phospholipase A2 towards phospholipids of egg-yolk emulsions. When the ability to inhibit the activity of Penicillium notatum phospholipase B towards mixed micelles of phosphatidylcholine and Triton X-100 was investigated, polymyxin B was found to be inhibitory while chloramphenicol and carbenicillin were found to stimulate the activity of the phospholipase. The activity of Bacillus cereus phospholipase C towards the mixed micelles was inhibited by bleomycin, oleandomycin and chloramphenicol. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：734 / 739

页数：6

共 15 条

[1] PHOSPHOLIPASE INACTIVATION INDUCED BY AN AMINO-PIPERAZINE DERIVATIVE - STUDY AT LIPID-WATER INTERFACE [J].