SERUM IRON AND TRANSFERRIN IN ACUTE NEUROLEPTIC INDUCED AKATHISIA

被引:26
作者
OLOUGHLIN, V [1 ]
DICKIE, AC [1 ]
EBMEIER, KP [1 ]
机构
[1] UNIV ABERDEEN,ABERDEEN DEPT MENTAL HLTH,ABERDEEN AB9 1FX,SCOTLAND
关键词
D O I
10.1136/jnnp.54.4.363
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Thirty acute psychiatric patients were examined prospectively at the beginning of neuroleptic treatment for acute psychotic symptoms and on average 16 days later. Two alternative hypotheses were examined: 1) neuroleptic treatment affects the levels of serum iron and transferrin; 2) acute akathisia developing during the initial few weeks of treatment is associated with low levels of serum iron and transferrin, either initially or at follow up or both. Serum iron levels did not change on repeat measurement, while there was a small, but significant decrease of serum transferrin. There was a significantly greater decrease in iron and transferrin levels in patients with akathisia on follow up compared with non-akathisics. In addition, akathisia ratings were highly correlated with serum transferrin levels on follow up.
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页码:363 / 364
页数:2
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